Body Kines and Organ Crosstalks: A Mini Review

Nabil Kamal Elnaggar; Mohamed Nabil Elnaggar

doi:doi:10.11648/j.ijde.20251002.13

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Body Kines and Organ Crosstalks: A Mini Review

Nabil Kamal Elnaggar^*, Mohamed Nabil Elnaggar

Published in International Journal of Diabetes and Endocrinology (Volume 10, Issue 2)

Received: 9 April 2025 Accepted: 29 April 2025 Published: 29 May 2025

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Abstract

Multiple organs are recently being recognized as having endocrine functions through their release of different hormones and proteins that are responsible for biologically interrelated and inter-connected signaling processes. Diabetes and other chronic diseases are subject to be influenced by these products where modulation or change of their function could take place due to alterations in the signaling processes affected by the secretion of these products In this mini review we tried to take a closer look at how these proteins referred to as “kines” which are considered as the leaders of communication will help the crosstalk between different tissues and it is of utmost important to discover in what way they can do that,. We will review the multiple and complex ways by which kines affect the physiological and pathological processes through reviewing what had been published of the works dealing with the action of different kines and what are the main organs that produce them although a great number of them had not yet been discovered or studied exclusively. The deep identification of their roles in health and diseases will pave the way for the pharmaceutical industry to innovate new drugs that will target their action towards a better organ harmony for the benefits of the patients.

Published in	International Journal of Diabetes and Endocrinology (Volume 10, Issue 2)
DOI	10.11648/j.ijde.20251002.13
Page(s)	45-53
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2025. Published by Science Publishing Group

Keywords

Kines, Myokines, Adiponectin, Osteocalcine, Hepatokines, Insulin Resistance

References

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APA Style

Elnaggar, N. K., Elnaggar, M. N. (2025). Body Kines and Organ Crosstalks: A Mini Review. International Journal of Diabetes and Endocrinology, 10(2), 45-53. https://doi.org/10.11648/j.ijde.20251002.13

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ACS Style

Elnaggar, N. K.; Elnaggar, M. N. Body Kines and Organ Crosstalks: A Mini Review. Int. J. Diabetes Endocrinol. 2025, 10(2), 45-53. doi: 10.11648/j.ijde.20251002.13

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AMA Style

Elnaggar NK, Elnaggar MN. Body Kines and Organ Crosstalks: A Mini Review. Int J Diabetes Endocrinol. 2025;10(2):45-53. doi: 10.11648/j.ijde.20251002.13

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@article{10.11648/j.ijde.20251002.13,
  author = {Nabil Kamal Elnaggar and Mohamed Nabil Elnaggar},
  title = {Body Kines and Organ Crosstalks: A Mini Review
},
  journal = {International Journal of Diabetes and Endocrinology},
  volume = {10},
  number = {2},
  pages = {45-53},
  doi = {10.11648/j.ijde.20251002.13},
  url = {https://doi.org/10.11648/j.ijde.20251002.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijde.20251002.13},
  abstract = {Multiple organs are recently being recognized as having endocrine functions through their release of different hormones and proteins that are responsible for biologically interrelated and inter-connected signaling processes. Diabetes and other chronic diseases are subject to be influenced by these products where modulation or change of their function could take place due to alterations in the signaling processes affected by the secretion of these products In this mini review we tried to take a closer look at how these proteins referred to as “kines” which are considered as the leaders of communication will help the crosstalk between different tissues and it is of utmost important to discover in what way they can do that,. We will review the multiple and complex ways by which kines affect the physiological and pathological processes through reviewing what had been published of the works dealing with the action of different kines and what are the main organs that produce them although a great number of them had not yet been discovered or studied exclusively. The deep identification of their roles in health and diseases will pave the way for the pharmaceutical industry to innovate new drugs that will target their action towards a better organ harmony for the benefits of the patients.
},
 year = {2025}
}

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TY  - JOUR
T1  - Body Kines and Organ Crosstalks: A Mini Review

AU  - Nabil Kamal Elnaggar
AU  - Mohamed Nabil Elnaggar
Y1  - 2025/05/29
PY  - 2025
N1  - https://doi.org/10.11648/j.ijde.20251002.13
DO  - 10.11648/j.ijde.20251002.13
T2  - International Journal of Diabetes and Endocrinology
JF  - International Journal of Diabetes and Endocrinology
JO  - International Journal of Diabetes and Endocrinology
SP  - 45
EP  - 53
PB  - Science Publishing Group
SN  - 2640-1371
UR  - https://doi.org/10.11648/j.ijde.20251002.13
AB  - Multiple organs are recently being recognized as having endocrine functions through their release of different hormones and proteins that are responsible for biologically interrelated and inter-connected signaling processes. Diabetes and other chronic diseases are subject to be influenced by these products where modulation or change of their function could take place due to alterations in the signaling processes affected by the secretion of these products In this mini review we tried to take a closer look at how these proteins referred to as “kines” which are considered as the leaders of communication will help the crosstalk between different tissues and it is of utmost important to discover in what way they can do that,. We will review the multiple and complex ways by which kines affect the physiological and pathological processes through reviewing what had been published of the works dealing with the action of different kines and what are the main organs that produce them although a great number of them had not yet been discovered or studied exclusively. The deep identification of their roles in health and diseases will pave the way for the pharmaceutical industry to innovate new drugs that will target their action towards a better organ harmony for the benefits of the patients.

VL  - 10
IS  - 2
ER  -

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Author Information

Nabil Kamal Elnaggar

Diabetes, Obesity and Endocrinology Center, Andalusia Hospitals, Alexandria, Egypt

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Mohamed Nabil Elnaggar

Department of Endocrinology, Diabetes and Metabolism, University Hospitals of Morecambe Bay NHS Foundation Trust, Lancaster, United Kingdom

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Plain Text BibTeX RIS

APA Style

Elnaggar, N. K., Elnaggar, M. N. (2025). Body Kines and Organ Crosstalks: A Mini Review. International Journal of Diabetes and Endocrinology, 10(2), 45-53. https://doi.org/10.11648/j.ijde.20251002.13

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ACS Style

Elnaggar, N. K.; Elnaggar, M. N. Body Kines and Organ Crosstalks: A Mini Review. Int. J. Diabetes Endocrinol. 2025, 10(2), 45-53. doi: 10.11648/j.ijde.20251002.13

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AMA Style

Elnaggar NK, Elnaggar MN. Body Kines and Organ Crosstalks: A Mini Review. Int J Diabetes Endocrinol. 2025;10(2):45-53. doi: 10.11648/j.ijde.20251002.13

Copy | Download

@article{10.11648/j.ijde.20251002.13,
  author = {Nabil Kamal Elnaggar and Mohamed Nabil Elnaggar},
  title = {Body Kines and Organ Crosstalks: A Mini Review
},
  journal = {International Journal of Diabetes and Endocrinology},
  volume = {10},
  number = {2},
  pages = {45-53},
  doi = {10.11648/j.ijde.20251002.13},
  url = {https://doi.org/10.11648/j.ijde.20251002.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijde.20251002.13},
  abstract = {Multiple organs are recently being recognized as having endocrine functions through their release of different hormones and proteins that are responsible for biologically interrelated and inter-connected signaling processes. Diabetes and other chronic diseases are subject to be influenced by these products where modulation or change of their function could take place due to alterations in the signaling processes affected by the secretion of these products In this mini review we tried to take a closer look at how these proteins referred to as “kines” which are considered as the leaders of communication will help the crosstalk between different tissues and it is of utmost important to discover in what way they can do that,. We will review the multiple and complex ways by which kines affect the physiological and pathological processes through reviewing what had been published of the works dealing with the action of different kines and what are the main organs that produce them although a great number of them had not yet been discovered or studied exclusively. The deep identification of their roles in health and diseases will pave the way for the pharmaceutical industry to innovate new drugs that will target their action towards a better organ harmony for the benefits of the patients.
},
 year = {2025}
}

Copy | Download

TY  - JOUR
T1  - Body Kines and Organ Crosstalks: A Mini Review

AU  - Nabil Kamal Elnaggar
AU  - Mohamed Nabil Elnaggar
Y1  - 2025/05/29
PY  - 2025
N1  - https://doi.org/10.11648/j.ijde.20251002.13
DO  - 10.11648/j.ijde.20251002.13
T2  - International Journal of Diabetes and Endocrinology
JF  - International Journal of Diabetes and Endocrinology
JO  - International Journal of Diabetes and Endocrinology
SP  - 45
EP  - 53
PB  - Science Publishing Group
SN  - 2640-1371
UR  - https://doi.org/10.11648/j.ijde.20251002.13
AB  - Multiple organs are recently being recognized as having endocrine functions through their release of different hormones and proteins that are responsible for biologically interrelated and inter-connected signaling processes. Diabetes and other chronic diseases are subject to be influenced by these products where modulation or change of their function could take place due to alterations in the signaling processes affected by the secretion of these products In this mini review we tried to take a closer look at how these proteins referred to as “kines” which are considered as the leaders of communication will help the crosstalk between different tissues and it is of utmost important to discover in what way they can do that,. We will review the multiple and complex ways by which kines affect the physiological and pathological processes through reviewing what had been published of the works dealing with the action of different kines and what are the main organs that produce them although a great number of them had not yet been discovered or studied exclusively. The deep identification of their roles in health and diseases will pave the way for the pharmaceutical industry to innovate new drugs that will target their action towards a better organ harmony for the benefits of the patients.

VL  - 10
IS  - 2
ER  -

Copy | Download