International Journal of Diabetes and Endocrinology

Volume 2, Issue 2, June 2017

  • Biochemical Profile and Genetic Polymorphism of MTHFRC677T in Risk of Type 2 Diabetes Mellituss

    Mushtaq Ahmad Bhat, Showkat Ahmad Bhat, Sheikh Bilal Ahmad, Wasim Qureshi, Sabhiya Majid, Aarif Ali, Ishraq Hussain, Tehseen Hassan, Muneeb U. Rehman, Manzoor R. Mir

    Issue: Volume 2, Issue 2, June 2017
    Pages: 19-25
    Received: Dec. 26, 2016
    Accepted: Mar. 17, 2017
    Published: Apr. 11, 2017
    DOI: 10.11648/j.ijde.20170202.11
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    Abstract: Diabetes mellitus (DM) is a common endocrine metabolic disorder and a leading cause of death worldwide Diabetes type-2 is a multicausal disease which develops slowly and in a stepwise order. Our study showed there was no significant difference in serum high density lipoprotein (HDL) and Tri glyceride (TG) of patients and controls (0.90±0.59 vs 1.15... Show More
  • Genetic Polymorphism and Personalized Medicine-Application in Metabolic Syndrome

    Ri-Hyang Paek, Dae-Yong Jon, Hak-Chol Ri, Yong-Ju Gong

    Issue: Volume 2, Issue 2, June 2017
    Pages: 26-29
    Received: Feb. 24, 2017
    Accepted: Apr. 01, 2017
    Published: May 18, 2017
    DOI: 10.11648/j.ijde.20170202.12
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    Abstract: To explore the associations between the phenotypes of metabolic syndrome and several genetic polymorphisms in the people of the Democratic People’s Republic of Korea, and to address the basic and practical problems that arise in carrying out the personalized medicine of metabolic syndrome. We analyzed the four phenotypes of metabolic syndrome inclu... Show More
  • Preventive Effect of Phloretin on Components of Glycoprotein Changes in Streptozotocin Induced Diabetic Rats

    Tamilarasan Nithiya, Rajangam Udayakumar

    Issue: Volume 2, Issue 2, June 2017
    Pages: 30-35
    Received: Feb. 28, 2017
    Accepted: Apr. 28, 2017
    Published: Jul. 03, 2017
    DOI: 10.11648/j.ijde.20170202.13
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    Abstract: The present study was aimed to evaluate the protective effect of phloretin on glycoprotein components in serum and tissues of streptozotocin induced diabetic rats. Diabetes was induced in male Wistar rats by a single intraperitoneal injection of STZ (60 mg/kg b.w). Phloretin (25mg and 50mg/kg b.w) was administered orally to diabetic rats for 45 day... Show More