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Effect of Exercise and Non-exercise Interventions on Cardiac Angiogenesis in Diabetes Mellitus Patients: A Review
Issue:
Volume 7, Issue 1, March 2022
Pages:
1-12
Received:
9 December 2021
Accepted:
5 January 2022
Published:
17 January 2022
Abstract: Background: It has been shown that about 80% of deaths in diabetic patients are due to cardiovascular disorders, which are called Diabetic Heart Disease or DHD, the most important of which are dysfunction and vascular damage, and consequently the stopping of coronary angiogenesis. Despite the many advances made in the field of medical research and the long-standing clinical history of diabetes mellitus, the risk of cardiovascular disease associated with diabetes has not been reduced. Method: Our search was performed by typing the words HIIT, MICT, Diabetic Heart Disease, MicroRNA, Cardiac Angiogenesis in pubmed. We reviewed the literature using articles that were relevant to our field of work. conclusion: Researchers have proposed different exercise programs to improve cardiovascular complications in diabetic patient, and their prominent role in improving the complications associated with microangiopathy compared to non-exercise interventions (hormone, complementary therapies, pharmaceutical methods, etc.) in these proven patients. but so far no study has been done to compare the effectiveness of exercise or non-exercise interventions on the improvement of microvascular complications in DHD patients. Therefore, this review article compares the types of interventions that affect the angiogenesis of patients with a history of DHD.
Abstract: Background: It has been shown that about 80% of deaths in diabetic patients are due to cardiovascular disorders, which are called Diabetic Heart Disease or DHD, the most important of which are dysfunction and vascular damage, and consequently the stopping of coronary angiogenesis. Despite the many advances made in the field of medical research and ...
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A Case of Secondary Hypogonadism with Increased Risk of Fractures in a 57-year-old Male Patient on Methadone Maintenance Therapy
Mario Sebastian Campana,
Maria Riofrio,
Raja Jadav,
Guido Macchiavello
Issue:
Volume 7, Issue 1, March 2022
Pages:
13-17
Received:
4 December 2021
Accepted:
14 January 2022
Published:
20 January 2022
Abstract: Oral maintenance opioid agonists have an important role in the management of heroin addiction and chronic pain. Methadone is one of the most popular and effective treatments for opioid dependence, however many patients following methadone’s clinics can develop a few metabolic and sexual side effects. Methadone can induce a few hormonal disbalance over time, including hypogonadotropic hypogonadism with sexual dysfunction, muscle weakness, and decreased bone mass density. Most of the side effects are dose-related especially when methadone is above 100 mg daily. Low levels of testosterone increase the risk of erectile dysfunction, loss of libido, sexual unsatisfaction, osteopenia, and osteoporosis, giving a poor quality of life in patients on methadone maintenance therapy. We present a case of a 57 -year-old male patient complaining about erectile dysfunction and loss of libido secondary to central hypogonadism induced by methadone with decreased bone density. The purpose of this case report is to bring these patients to the primary care world and improve their management with a multidisciplinary team including primary care, endocrinologists, and psychologists. Physicians should be aware of opioid-induced endocrinopathies and address properly with early sex hormones work up, bone density screening, and encourage methadone tapering every visit.
Abstract: Oral maintenance opioid agonists have an important role in the management of heroin addiction and chronic pain. Methadone is one of the most popular and effective treatments for opioid dependence, however many patients following methadone’s clinics can develop a few metabolic and sexual side effects. Methadone can induce a few hormonal disbalance o...
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Diabetic-Mellitus as an Etiological Factor in Hearing Loss
Jeevan Jyoti,
Younus Majeed Dar,
Shahnaz Ahmed Mir,
Ihsan Ali
Issue:
Volume 7, Issue 1, March 2022
Pages:
18-21
Received:
27 November 2021
Accepted:
7 January 2022
Published:
3 March 2022
Abstract: Background: The association of sensorineural hearing loss (SNHL) in diabetes mellitus patients is known since decades, yet there is no clear consensus among previous studies, with respect to the prevalence of SNHL in type 2 diabetes patients and the effect of duration and control of diabetes on hearing acuity. Hence the objectives of this study are to find the prevalence of SNHL in type 2 diabetes patients and to find the effect of duration and control of diabetes on hearing loss. Methods: The present study was conducted on 100 type 2 diabetes patients and age and gender matched 100 non- diabetic controls in the age group of < 50 yrs, selected based on inclusion and exclusion criteria. After detailed history taking and clinical examination, all subjects underwent FBS, PPBS estimation and HbA1c evaluation was done for diabetic patients. All underwent pure tone audiometry, DPOAE and BERA and the findings were recorded and analyzed. Results: Diabetes patients had insidious onset, gradually progressive, bilaterally symmetrical SNHL. SNHL is prevalent in 73% of type 2 diabetes patients compared to 16% of controls. It is aggravated with the increasing age and duration of diabetes. Poor control of diabetes showed increased prevalence of SNHL compared to good control of diabetes. Conclusions: There is increased prevalence of SNHL in type 2 diabetes patients and it is more evident in patients with long duration of diabetes and more pronounced in patients with poor diabetic control.
Abstract: Background: The association of sensorineural hearing loss (SNHL) in diabetes mellitus patients is known since decades, yet there is no clear consensus among previous studies, with respect to the prevalence of SNHL in type 2 diabetes patients and the effect of duration and control of diabetes on hearing acuity. Hence the objectives of this study are...
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