International Journal of Diabetes and Endocrinology

Volume 6, Issue 4, December 2021

  • Factors of Non-adherence to Antidiabetic Drugs in Type 2 Diabetics, Antananarivo Madagascar

    Sitraka Angelo Raharinavalona, Rija Eric Raherison, Thierry Razanamparany, Solofo Andrianarivelo Ralamboson, Andrinirina Dave Patrick Rakotomalala, Hanta Marie Danielle Vololontiana, Radonirina Lazasoa Andrianasolo

    Issue: Volume 6, Issue 4, December 2021
    Pages: 125-130
    Received: Aug. 14, 2021
    Accepted: Sep. 06, 2021
    Published: Oct. 12, 2021
    Downloads:
    Views:
    Abstract: Introduction: The non-adherence to therapy of diabetics is grafted with heavy morbidity and mortality. Our study aims to determine the factors of non-adherence with antidiabetic drugs in type 2 diabetics. Methods: This was a descriptive and analytical cross-sectional study, carried out in the Endocrinology Unit of the Joseph Raseta University Hospi... Show More
  • Evaluation of C-peptide in Type 2 Diabetic Patients in Douala Cameroon: C-peptide Correlation with Arterial Hypertension and the Types of Treatment Administered

    Manta Diane, Mbango-Ekouta Noel Désirée, Nda Mefo'o Jean Pierre, Assiene Oyong Damase Serge, Eloumou Bagnaka Servais, Adiogo Dieudonné

    Issue: Volume 6, Issue 4, December 2021
    Pages: 131-133
    Received: Aug. 17, 2021
    Accepted: Oct. 16, 2021
    Published: Oct. 28, 2021
    Downloads:
    Views:
    Abstract: Introduction: C-peptide is the best indicator of endogenous insulin secretion; it makes it possible to optimize the treatment, and to prevent the occurrence and the evolution of the damages resulting from type 2 diabetes. The present study reports the variation of C-peptide levels according to the types of treatment administrated and the high blood... Show More
  • The Prevalence of Type 2 Diabetes in the 27 Local Government Areas (LGAs) of Imo State

    Nwaokoro Joakin Chidozie, Onwuliri Viola Adaku, Onyeocha Ignatius, Onwuliri Daniel Chinemerem, Nnodim Johnkennedy, Ede Okorie Alison

    Issue: Volume 6, Issue 4, December 2021
    Pages: 134-141
    Received: May 24, 2021
    Accepted: Jul. 07, 2021
    Published: Nov. 23, 2021
    Downloads:
    Views:
    Abstract: Diabetes is a homeostasis imbalance in which insulin is deficient. It poses a great public problem and economic cost. This study investigated prevalence of type 2 diabetes in Imo State, Southeastern Nigeria. Sample size consisted 3690 persons from across the state. Research instrument for data collection were questionnaires and test kits for blood ... Show More
  • The Incident Pattern and Trend of Type 2 Diabetes Among Adults in Akwa Ibom State, South-south Nigeria

    Collins Amadi, Samuel Onung, Olufisayo Ayoade, Emmanuel Abudu, Fabian Unyime, Anthony Usoro

    Issue: Volume 6, Issue 4, December 2021
    Pages: 142-149
    Received: Oct. 31, 2021
    Accepted: Nov. 16, 2021
    Published: Nov. 23, 2021
    Downloads:
    Views:
    Abstract: Background: Epidemiologic data indicate that the incident characteristics of type 2 diabetes mellitus (T2DM) are proper metrics to accurately define the true trajectory of the metabolic disorder. However, this is poorly characterized among Nigerians with T2DM. Hence, the current study evaluated the incident characteristics (pattern/trend) of T2DM a... Show More
  • Early-stage Hyperglycemia-induced Gut Microbial Changes Are Partially Associated with Mechanical Allodynia in db/db Mice

    Xinting Wang, Jihong Wu, Simin Qi, Rui Huang, Xiaoping Wu, Lin Tian, Peili Wang, Shenglan Wang

    Issue: Volume 6, Issue 4, December 2021
    Pages: 150-159
    Received: Oct. 27, 2021
    Accepted: Nov. 22, 2021
    Published: Dec. 02, 2021
    Downloads:
    Views:
    Abstract: Recent studies have demonstrated that pain is partially regulated by the gut microbiota. However, the association of gut microbiota with painful diabetic neuropathy, a common complication of diabetes, remains unclear. Herein, we investigated whether the gut microbiota is associated with mechanical allodynia during the early stage of hyperglycemia i... Show More
  • Clinical and Biochemical Parameters at Presentation of Patients with Adrenal Insufficiency Attending a Tertiary Care Hospital

    Rezwana Sobhan, Khan Mohammad Nazmus Saqeb, Mohammad Ibrahim, Aleya Ferdush Monni, Mohammad Faruque Pathan, Mohammad Ashrafuzzaman

    Issue: Volume 6, Issue 4, December 2021
    Pages: 160-166
    Received: Oct. 30, 2021
    Accepted: Nov. 17, 2021
    Published: Dec. 24, 2021
    Downloads:
    Views:
    Abstract: Background: Adrenal insufficiency is the clinical manifestation of deficient production or action of glucocorticoids, with or without deficiency of mineralocorticoids and adrenal androgens. It results from primary adrenal failure or secondary adrenal disease due to impairment of the hypothalamic–pituitary axis. Patients often have nonspecific sympt... Show More
  • Semaglutide as an Antidiabetic Medication: A Summary of the Evidence from the Semaglutide Unabated Sustainability in Treatment of Type 2 Diabetes Clinical Trial Program

    Gurdeep Singh, Matthew Krauthamer, Meghan Bjalme-Evans

    Issue: Volume 6, Issue 4, December 2021
    Pages: 167-174
    Received: Nov. 27, 2021
    Accepted: Dec. 14, 2021
    Published: Dec. 24, 2021
    Downloads:
    Views:
    Abstract: Background: The Semaglutide Unabated Sustainability in Treatment of Type 2 Diabetes (SUSTAIN) clinical trial program was a phase III, multinational, multicenter program comprising 13 trials. Objective: Investigate the safety and efficacy of once-weekly, subcutaneous semaglutide versus other antidiabetic comparators, both as a monotherapy and in add... Show More