Research Article
Evaluation of Procalcitonin in Type-2 Diabetes Mellitus Patients in Minahasa, North Sulawesi, Indonesia
Issue:
Volume 9, Issue 4, December 2024
Pages:
65-70
Received:
1 October 2024
Accepted:
23 October 2024
Published:
12 November 2024
DOI:
10.11648/j.ijde.20240904.11
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Abstract: Diabetes mellitus (DM) remains a significant global health challenge, contributing to high morbidity and mortality rates. In Indonesia, type 2 diabetes is increasing, with a substantial percentage of patients experiencing poor glycemic control. This study aims to explore the relationship between serum procalcitonin levels and fasting blood glucose (FBG) in patients with type 2 diabetes, assessing procalcitonin's potential as a biomarker for diabetes complications. A total of 122 patients with confirmed type 2 diabetes were included, excluding those with infection or recent trauma. Clinical parameters, including blood pressures, body mass index (BMI), and blood samples for FBG and procalcitonin levels, were collected. Statistical analysis was performed using SPSS version 26.0. The mean age of participants was 56.7 years, with 43.4% diagnosed with hypertension. A significant correlation was found between procalcitonin and FBG (p = 0.024, r = 0.205), indicating a weak positive relationship. No significant differences in procalcitonin levels were observed between hypertensive and non-hypertensive patients. The findings suggest that procalcitonin may serve as a useful biomarker in managing complications associated with type 2 diabetes. While the correlation with FBG was weak, the role of inflammation in diabetes progression highlights the need for further investigation. Integrating procalcitonin testing into clinical practice could enhance patient management, and future research should explore the mechanisms linking procalcitonin levels to diabetes complications, as well as establish reference values for procalcitonin in diabetic populations.
Abstract: Diabetes mellitus (DM) remains a significant global health challenge, contributing to high morbidity and mortality rates. In Indonesia, type 2 diabetes is increasing, with a substantial percentage of patients experiencing poor glycemic control. This study aims to explore the relationship between serum procalcitonin levels and fasting blood glucose ...
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Case Report
Exploring the Link Between Diabetes and Striatopathy: A Case Report
Janushee Modi
,
Vismit Gami,
Tushar Teraiya,
Sahil Shah,
Dev Desai*
Issue:
Volume 9, Issue 4, December 2024
Pages:
71-74
Received:
9 September 2024
Accepted:
29 September 2024
Published:
13 November 2024
Abstract: Diabetic striatopathy (DS) is known as a hyperglycemia-based chorea/ballism. Its classical demonstration is striatal hyper density on computed tomography, or hyperintensity on T1- weighted magnetic resonance imaging. It characterises a somewhat rare hyperglycemia condition that is linked to hyperdensity on computed tomography (CT) and/or hyperintensity on T1-weighted nuclear magnetic resonance imaging (MRI) as well as chorea/ballism and basal ganglia. Patients having a hyperglycaemic condition linked to even one of the following would also be included in DS, per a recent systematic study: (1) ballet or chorea; hyperintensity on T1-weighted MRI or (2) striatal hyperdensity in CT. Additionally, there has been a recent proposal for a potential categorisation of DS. There aren't many case series on this subject that have been documented in the literature yet. It is thought that the prevalence of DS, which has been reported to be 1 in 100,00010, is underreported since most doctors are unaware of the disorder and may mistake it for typical intracerebral hemorrhage. It has been shown that older women with type 2 diabetes mellitus (DM) are more likely to develop the disease. Here, we describe an acute case of DS along with its characteristic radiological features, clinical presentation, imaging and instrumental exams, and treatment strategy. This case report serves as a helpful reminder to medical professionals to take diabetes patients with poor control into account when they exhibit symptoms including altered sensorium, sudden-onset choreiform movement, and ballistic motions.
Abstract: Diabetic striatopathy (DS) is known as a hyperglycemia-based chorea/ballism. Its classical demonstration is striatal hyper density on computed tomography, or hyperintensity on T1- weighted magnetic resonance imaging. It characterises a somewhat rare hyperglycemia condition that is linked to hyperdensity on computed tomography (CT) and/or hyperinten...
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